Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:175589 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
175589176128540hypothetical proteinBLASTP
1761101784402331cation-transporting P-type ATPaseQuickGO ontologyBLASTP
178536178832297hypothetical protein
1792331811911959hypothetical proteinBLASTP
181470181589120hypothetical protein
181586181723138hypothetical protein
181764181910147luciferase-like proteinQuickGO ontologyBLASTP
182039182191153hypothetical proteinBLASTP
182314182457144hypothetical protein
182633182749117hypothetical protein
183795184073279hypothetical protein
184294184932639hypothetical protein
184997185902906LysR family transcriptional regulatorQuickGO ontologyBLASTP
186000186173174hypothetical protein
18632218639473tRNA-TrpQuickGO ontology
1865251877121188WD-40 repeat-containing proteinQuickGO ontologyBLASTP
188352188912561hypothetical protein
1893741922232850alpha-glucuronidaseQuickGO ontologyBLASTP
1924711935531083hypothetical proteinBLASTP
193534194376843antigen cfp29QuickGO ontologyBLASTP
194439195059621TetR family transcriptional regulatorQuickGO ontologyBLASTP
19605619614893hypothetical protein
196145196615471putative DNA-binding proteinQuickGO ontologyBLASTP
196668197195528acyl-CoA dehydrogenase domain-containing proteinQuickGO ontologyBLASTP
197199198008810dehydrogenaseQuickGO ontologyBLASTP