Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:1751988 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
175198817533671380hypothetical proteinBLASTP
175443517556551221putative metallophosphoesteraseQuickGO ontologyBLASTP
17560121756560549integrase catalytic regionQuickGO ontologyBLASTP
17563701757041672integrase catalytic regionQuickGO ontologyBLASTP
17573571757710354hypothetical proteinBLASTP
175782617590911266transposaseQuickGO ontologyBLASTP
17594551759676222transcriptional regulatorQuickGO ontologyBLASTP
17596761760161486transmembrane transport proteinQuickGO ontologyBLASTP
17604671760760294hypothetical proteinBLASTP
17609951761345351integrase catalytic regionQuickGO ontologyBLASTP
17621091763038930putative sugar transport integral membrane proteinQuickGO ontologyBLASTP
176305517640711017sugar transport permeaseQuickGO ontologyBLASTP
176416017654761317solute binding lipoproteinQuickGO ontologyBLASTP
176575217667681017LacI family transcriptional regulatorQuickGO ontologyBLASTP
17670411767985945integrase catalytic regionQuickGO ontologyBLASTP
17682271768655429hypothetical proteinBLASTP
17688941769280387metallothiol transferase fosBQuickGO ontologyBLASTP
17694381769788351antibiotic biosynthesis monooxygenaseQuickGO ontologyBLASTP
17700511770632582TetR-family protein transcriptional regulatorQuickGO ontologyBLASTP
17708801771029150hypothetical protein
17713311772044714hypothetical proteinBLASTP