Pre_GI Gene

Some Help

Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:11878078 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11878078118809182841sugar hydrolaseQuickGO ontologyBLASTP
11881182118834642283alpha-xylosidaseQuickGO ontologyBLASTP
118836111188368575alpha-xylosidaseQuickGO ontology
11884156118863572202hypothetical proteinBLASTP
11886728118878011074hypothetical proteinBLASTP
1188799811888642645integrase catalytic regionQuickGO ontologyBLASTP
1188864411888865222putative transposaseQuickGO ontologyBLASTP
1188889311889768876putative oxidoreductaseQuickGO ontologyBLASTP
1189219711892538342hypothetical proteinBLASTP
1189302411893827804integrase catalytic regionQuickGO ontologyBLASTP
1189399811894132135hypothetical proteinBLASTP
1189432111894485165hypothetical proteinBLASTP
1189474011895285546hypothetical protein
11895490118978922403hypothetical protein
1189922911899624396transposaseQuickGO ontologyBLASTP
1189988611900347462transposaseQuickGO ontologyBLASTP
1190041811901173756putative oxidoreductaseQuickGO ontologyBLASTP
1190130211901736435hypothetical proteinBLASTP
1190194311902323381IS1648-like transposaseQuickGO ontologyBLASTP
1190230211902730429putative transposase IS4QuickGO ontologyBLASTP
1190531411905994681two-component system response regulatorQuickGO ontologyBLASTP
11906020119074951476two-component system sensor kinaseQuickGO ontologyBLASTP