Pre_GI Gene

Some Help

Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:11820671 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11820671118222781608Ricin B lectinQuickGO ontologyBLASTP
1182232011822457138hypothetical protein
11822577118248862310hypothetical proteinBLASTP
1182495611825951996endo-14-beta-xylanaseQuickGO ontologyBLASTP
1182596111826425465hypothetical protein
1182642711827215789hypothetical proteinBLASTP
11827257118292361980putative glycosyl hydrolaseQuickGO ontologyBLASTP
11829345118309371593extracellular solute-binding proteinQuickGO ontologyBLASTP
1183104711831901855binding-protein-dependent transport system inner membrane proteinQuickGO ontologyBLASTP
1183204811833007960binding-protein-dependent transport system inner membrane proteinQuickGO ontologyBLASTP
1183457511835534960LacI family transcriptional regulatorQuickGO ontologyBLASTP
1183572211836663942glycosyl transferase family proteinQuickGO ontologyBLASTP
11837016118398922877glycoside hydrolase family proteinQuickGO ontologyBLASTP
11840011118415371527putative transmembrane proteinQuickGO ontologyBLASTP
1184165511842452798GntR family transcriptional regulatorQuickGO ontologyBLASTP
11842831118441951365putative solute-binding lipoproteinQuickGO ontologyBLASTP
1184419211845106915hypothetical proteinBLASTP
1184509611845962867putative integral membrane transport proteinQuickGO ontologyBLASTP
11846123118480301908hypothetical protein
11848071118503652295hypothetical proteinBLASTP
1185162011851739120hypothetical protein
1185172011852556837glycoside hydrolase family proteinQuickGO ontologyBLASTP
1185269511853621927hypothetical protein
11853823118559252103putative beta-galactosidaseQuickGO ontologyBLASTP
11856298118578061509cellulose-binding family II proteinQuickGO ontologyBLASTP
1185781811857997180hypothetical protein
11858331118593711041transcriptional regulatorQuickGO ontologyBLASTP
11859415118611691755glycoside hydrolase family proteinQuickGO ontologyBLASTP
1186124111862221981putative transcriptional regulatorQuickGO ontologyBLASTP
1186247011863453984Acetyl xylan esteraseQuickGO ontologyBLASTP