Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:11734963 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1173496311735094132hypothetical protein
1173519611735456261hypothetical protein
1173559511735765171hypothetical protein
1173597411736168195hypothetical protein
1173664411736967324hypothetical protein
1173738511737585201hypothetical protein
1173767711738477801hypothetical proteinBLASTP
1173865411739217564hypothetical proteinBLASTP
1174081511741231417hypothetical protein
1174158511741767183hypothetical protein
1174192411742577654integrase catalytic subunitQuickGO ontologyBLASTP
1174300411743417414hypothetical protein
1174353911743766228hypothetical protein
1174413511744323189hypothetical protein
1174432311744661339putative hydrolaseQuickGO ontology
1174479011745230441hypothetical proteinBLASTP
1174558411746015432hypothetical proteinBLASTP
11745987117470871101putative transposase for insertion sequence elementQuickGO ontologyBLASTP
11746866117479061041putative transposaseQuickGO ontologyBLASTP
11748193117494011209glycoside hydrolase family proteinQuickGO ontologyBLASTP
1174976811750391624phage integrase family site specific recombinaseQuickGO ontologyBLASTP
1175041311750997585TetR family transcriptional regulatorQuickGO ontologyBLASTP
11751198117535522355MMPL domain-containing proteinQuickGO ontologyBLASTP