Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:11672500 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11673042116750512010beta-galactosidaseQuickGO ontologyBLASTP
11675118116761641047hypothetical proteinBLASTP
11676919116779351017putative acetyl esteraseQuickGO ontologyBLASTP
1167807611678315240putative ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
1167900011679203204site-specific recombinase integrase family proteinQuickGO ontologyBLASTP
1167936611680262897hypothetical proteinBLASTP
1168124811682057810hypothetical proteinBLASTP
1168225611683050795hypothetical proteinBLASTP
1168459511685488894alphabeta fold family hydrolaseQuickGO ontologyBLASTP
1168593511686417483hypothetical protein
1168741911688027609TetR family transcriptional regulatorQuickGO ontologyBLASTP
1168812111688861741short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
1168887711689536660NADP oxidoreductase coenzyme F420-dependentQuickGO ontologyBLASTP
1168965211690044393hypothetical proteinBLASTP
1169011111690797687short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP