Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:11380000 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1138040411381240837Short-chain dehydrogenase family proteinQuickGO ontologyBLASTP
1138125711382129873NmrA family proteinQuickGO ontologyBLASTP
1138221411383089876NmrA family proteinQuickGO ontologyBLASTP
1138315911383824666putative transcriptional regulatorQuickGO ontologyBLASTP
1138382111384117297hypothetical protein
1138440111384760360TetR family transcriptional regulatorQuickGO ontology
1138476611384942177hypothetical protein
1138501511385608594hypothetical proteinBLASTP
1138581911386454636hypothetical proteinBLASTP
1138658511387517933AraC family transcription regulatorQuickGO ontologyBLASTP
1138754911388190642TetR family transcriptional regulatorQuickGO ontologyBLASTP
11388451113897611311drug resistance transporter EmrBQacA subfamily proteinQuickGO ontologyBLASTP
11389758113913231566drug resistance transporter EmrBQacA subfamily proteinQuickGO ontologyBLASTP
1139157411392059486putative integral membrane proteinQuickGO ontologyBLASTP
1139219711393024828integral membrane proteinQuickGO ontologyBLASTP
1139319011394092903integral membrane proteinQuickGO ontologyBLASTP
11394073113957551683two-component system sensor kinaseQuickGO ontologyBLASTP
1139575211396414663two-component system response regulatorQuickGO ontologyBLASTP
1139668711396860174hypothetical protein
1139680811397740933hypothetical proteinBLASTP
1139773711398114378hypothetical proteinBLASTP
1139826711398932666hypothetical proteinBLASTP
1139892911399534606integral membrane proteinQuickGO ontologyBLASTP
11399668114008761209major facilitator superfamily transporterQuickGO ontologyBLASTP
1140137111401607237hypothetical proteinBLASTP
1140177111402694924beta-xylosidaseQuickGO ontologyBLASTP