Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10638524 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10638524106404641941Rhs element Vgr proteinQuickGO ontologyBLASTP
1064047210641287816Peptidoglycan-binding LysMQuickGO ontologyBLASTP
1064129610641733438hypothetical proteinBLASTP
1064175910641869111hypothetical protein
1064347510643618144hypothetical proteinBLASTP
1064361510644085471hypothetical proteinBLASTP
1064408510644528444hypothetical proteinBLASTP
10644561106461201560tail sheath proteinQuickGO ontologyBLASTP
10646554106501713618hypothetical proteinBLASTP
1065176310652041279hypothetical protein
1065205310652637585hypothetical protein
1065271210653239528hypothetical proteinBLASTP
1065361810653869252hypothetical proteinBLASTP
1065386910654015147hypothetical protein
1065430610655232927hypothetical proteinBLASTP
10655294106574802187AAA ATPaseQuickGO ontologyBLASTP
1065747710658202726hypothetical proteinBLASTP
10658211106608502640Na-Ca exchangerintegrin-beta4QuickGO ontologyBLASTP
1066100610661506501LuxR family transcriptional regulatorQuickGO ontologyBLASTP
10661898106632711374hypothetical protein
1066332210664149828hypothetical proteinBLASTP