Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10326938 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10326938103281341197secreted proteinQuickGO ontology
10328233103292881056integrase catalytic regionQuickGO ontologyBLASTP
1032934310329486144hypothetical proteinBLASTP
1032950810329771264integrase catalytic regionQuickGO ontologyBLASTP
1032999710330221225hypothetical protein
1033035010330619270hypothetical protein
10332427103336231197IS116IS110IS902 family transposaseQuickGO ontologyBLASTP
1033368110334139459hypothetical proteinBLASTP
1033425510334638384putative transposaseQuickGO ontologyBLASTP
1033775810338366609hypothetical proteinBLASTP
1033882210339559738integrase catalytic regionQuickGO ontologyBLASTP
10339945103410241080integrase catalytic regionQuickGO ontologyBLASTP
1034236810342805438hypothetical proteinBLASTP
1034373810344244507hypothetical proteinBLASTP
1034437110344721351transposase IS4QuickGO ontologyBLASTP
1034474710345025279hypothetical proteinBLASTP
1034502210345414393hypothetical proteinBLASTP
1034548510346480996hypothetical proteinBLASTP
1034667810347607930integrase catalytic regionQuickGO ontologyBLASTP
1034792310348282360transposase IS204IS1001IS1096IS1165 family proteinQuickGO ontologyBLASTP
1034835210348477126hypothetical protein
103485421034965111102-dehydropantoate 2-reductaseQuickGO ontologyBLASTP
10349548103508311284putative MFS transporterQuickGO ontologyBLASTP
1035090810351474567transcriptional regulatorQuickGO ontologyBLASTP
1035206810352817750hypothetical proteinBLASTP
1035369910354004306DNA-binding proteinQuickGO ontologyBLASTP
1035400110354384384hypothetical proteinBLASTP
10355650103567411092integrase catalytic subunitQuickGO ontologyBLASTP
1035762410358232609CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseQuickGO ontologyBLASTP