Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10287865 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10287865102895441680malate dehydrogenaseQuickGO ontologyBLASTP
1028965810290098441hypothetical protein
1029018710290933747maleate cis-trans isomeraseQuickGO ontologyBLASTP
1029094310291848906alphabeta hydrolase fold proteinQuickGO ontology
1029185510292607753acetoacetate decarboxylaseQuickGO ontologyBLASTP
10292621102937991179homogentisate 12-dioxygenaseQuickGO ontologyBLASTP
10293846102951621317hypothetical proteinBLASTP
1029534110296162822GntR family transcriptional regulatorQuickGO ontology
1029644010296799360putative HTH-type transcriptional regulatorQuickGO ontologyBLASTP
1029715910297608450hypothetical protein
1029780510298467663TetR family transcriptional regulatorQuickGO ontologyBLASTP
10298958103005351578cytochrome B subunitQuickGO ontologyBLASTP
10301332103034102079superfamily I DNA and RNA helicase-like proteinQuickGO ontologyBLASTP
1030349810303797300hypothetical proteinBLASTP
103040741030476669334-dihydroxyphenylacetate 23-dioxygenaseQuickGO ontologyBLASTP
1030503210305622591putative transcriptional regulatorQuickGO ontologyBLASTP
10305728103070591332putative carboxyesteraseQuickGO ontologyBLASTP