Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10159486 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1015849710159489993SPDB2 proteinQuickGO ontologyBLASTP
1015948610160439954NLPP60 proteinQuickGO ontologyBLASTP
10160439101614491011hypothetical proteinBLASTP
10161515101639262412hypothetical proteinBLASTP
10163914101657731860type IV secretory pathway VirB4 protein-like proteinQuickGO ontologyBLASTP
1016577010166723954hypothetical proteinBLASTP
10166724101682621539hypothetical proteinBLASTP
1016863710169014378hypothetical proteinBLASTP
1016933510170108774hypothetical proteinBLASTP
1017057510171234660hypothetical protein
1017125010172203954putative RNA methylaseQuickGO ontologyBLASTP
10173038101742641227hypothetical proteinBLASTP
1017433110174783453secreted proteinQuickGO ontologyBLASTP
1017493310175589657hypothetical protein
1017558610176125540ECF subfamily RNA polymerase sigma factorQuickGO ontologyBLASTP
1017615410176381228hypothetical protein
1017750410178073570putative secreted proteinQuickGO ontologyBLASTP
10178299101794501152hypothetical proteinBLASTP
1018017010181168999hypothetical protein
10181922101832801359NADPH-dependent glutamate synthase beta chainQuickGO ontologyBLASTP
1018394210184514573integrase catalytic regionQuickGO ontologyBLASTP
10184723101862851563transposase IS4 family proteinQuickGO ontologyBLASTP
10186457101878421386glycoside hydrolase family proteinQuickGO ontologyBLASTP
10188200101896001401putative hydrolaseQuickGO ontologyBLASTP
10189856101915021647putative glycosyl hydrolasexylanaseQuickGO ontologyBLASTP
1019200610192161156hypothetical protein
10192635101951662532FG-GAP repeat-containing proteinQuickGO ontologyBLASTP
10195300101970031704AcetyltransferaseQuickGO ontologyBLASTP
1019707110197988918binding-protein-dependent transport system inner membrane proteinQuickGO ontologyBLASTP
1019800310198944942binding-protein-dependent transport system inner membrane proteinQuickGO ontologyBLASTP
10198949102001241176extracellular solute-binding proteinQuickGO ontologyBLASTP
10200655102017971143LacI family transcriptional regulatorQuickGO ontologyBLASTP
102017941020279810052-hydroxyacid family dehydrogenaseQuickGO ontologyBLASTP
1020291310203428516integrase catalytic regionQuickGO ontologyBLASTP
1020331410204120807glycine cleavage T proteinQuickGO ontologyBLASTP
1020422010204462243hypothetical protein
10204462102060991638putative transmembrane efflux proteinQuickGO ontologyBLASTP
1020638710207364978AsnC family transcriptional regulatorQuickGO ontologyBLASTP
1020784110208386546hypothetical protein
1020856310209084522putative transposaseQuickGO ontologyBLASTP