Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10137951 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1013710910137954846hypothetical proteinBLASTP
10137951101393001350type II secretion system protein EQuickGO ontologyBLASTP
1013929710140211915putative integral membrane proteinQuickGO ontologyBLASTP
1014020810141107900type II secretion system proteinQuickGO ontologyBLASTP
1014117410141374201hypothetical protein
1014138710141782396hypothetical proteinBLASTP
1014183310142213381hypothetical proteinBLASTP
1014221010142659450hypothetical proteinBLASTP
10142698101454272730SARP family transcriptional regulatorQuickGO ontologyBLASTP
1014576210146406645putative glycosyl hydrolasexylanaseQuickGO ontologyBLASTP
1014664610147365720hypothetical proteinBLASTP
1014793910148754816regulatory proteinQuickGO ontologyBLASTP
10148842101506501809hypothetical proteinBLASTP
1015122510151935711hypothetical proteinBLASTP
1015204410152766723hypothetical proteinBLASTP
1015289110153535645hypothetical proteinBLASTP
1015357110153996426hypothetical proteinBLASTP
1015414710154644498hypothetical proteinBLASTP
1015501610155504489AsnC family transcriptional regulatorQuickGO ontologyBLASTP
10155680101571191440aromatic-L-amino-acid decarboxylaseQuickGO ontologyBLASTP