Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10104458 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10104458101076943237hypothetical proteinBLASTP
1010809610109037942hydrolaseQuickGO ontologyBLASTP
1010994010110185246hypothetical proteinBLASTP
1011035410110614261hypothetical proteinBLASTP
1011063310110989357integraseQuickGO ontologyBLASTP
1011146510111755291hypothetical protein
1011195010112456507Crp family transcriptional regulatorQuickGO ontologyBLASTP
1011261910113365747hypothetical proteinBLASTP
10113812101156351824hypothetical protein
1011568610116324639hypothetical protein
1011632110116548228hypothetical proteinBLASTP
10117905101189211017hypothetical proteinBLASTP
1011949010119624135hypothetical protein
1011962110119770150IS6 family transposaseQuickGO ontologyBLASTP
1012062210120783162hypothetical protein
1012099210121480489hypothetical protein
1012182110122009189hypothetical protein
1012201910122486468hypothetical proteinBLASTP
1012249210123442951hypothetical proteinBLASTP
1012352910123765237hypothetical proteinBLASTP
1012443610124936501putative transposaseQuickGO ontologyBLASTP
10124920101260591140hypothetical proteinBLASTP
1012625810126428171putative transposaseQuickGO ontologyBLASTP
1012840610128645240hypothetical protein
1012863010129421792helix-turn-helix domain-containing proteinQuickGO ontologyBLASTP
1012967210130220549hypothetical protein
1013079810131787990hypothetical proteinBLASTP
1013178410132323540acetyltransferaseQuickGO ontologyBLASTP
1013241310132964552hypothetical proteinBLASTP
1013328610133465180hypothetical protein
1013552110135673153hypothetical protein