Pre_GI Gene

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Host: NC_016582 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016582:10015558 Streptomyces bingchenggensis BCW-1 chromosome, complete genome

Host Lineage: Streptomyces bingchenggensis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Streptomyces bingchenggensis BCW-1 was isolated from a soil sample collected in Harbin, China. This species produces milbemycins, a family of macrocyclic lactones widely used in human health, animal health, and crop protection. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1001555810016244687hypothetical proteinBLASTP
10016385100177401356major facilitator superfamily proteinQuickGO ontologyBLASTP
1001778810018579792amidohydrolaseQuickGO ontologyBLASTP
1001857610018947372hypothetical proteinBLASTP
1001892210019551630GntR family transcriptional regulatorQuickGO ontologyBLASTP
1001988910020656768SARP family transcriptional regulatorQuickGO ontologyBLASTP
10021257100225641308manganese transport protein MntHQuickGO ontologyBLASTP
10022656100238071152bicupin oxalate decarboxylase family proteinQuickGO ontologyBLASTP
10024191100262512061magnesium or manganese-dependent protein phosphataseQuickGO ontologyBLASTP
1002665310026850198hypothetical protein
1002700010027419420hypothetical proteinBLASTP
1002741610027637222hypothetical protein
1002778310028238456hypothetical proteinBLASTP
10028557100312322676hypothetical proteinBLASTP
10031783100331201338hypothetical proteinBLASTP
1003343910034293855secreted proteinQuickGO ontologyBLASTP
1003441410034602189hypothetical proteinBLASTP
1003470410035363660hypothetical proteinBLASTP