Pre_GI Gene

Some Help

Host: NC_016516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016516:834260 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
834260835036777sortase family proteinQuickGO ontologyBLASTP
835361836857149730S ribosomal protein S1QuickGO ontologyBLASTP
8370788384811404HtaAQuickGO ontologyBLASTP
8386038397061104hemin receptorQuickGO ontologyBLASTP
8397038407641062Heme ABC transporter permease protein HmuUQuickGO ontologyBLASTP
840761841540780Heme ABC transporter ATPase component HmuVQuickGO ontologyBLASTP
8415438432731731ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8432708449401671ABC-type transport system fused ATPase and permeaseQuickGO ontologyBLASTP
844969845676708dephospho-CoA kinaseQuickGO ontologyBLASTP
8464948477651272htaaQuickGO ontologyBLASTP
848225849205981magnesium chelatase subunit ChlIQuickGO ontologyBLASTP
8492078510091803ATPase family associated with various cellular activities AAAQuickGO ontologyBLASTP
851009851422414hypothetical proteinBLASTP
8515788554113834CobNmagnesium chelatase domain proteinQuickGO ontologyBLASTP
855408856217810ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8562198572621044iron chelate uptake ABC transporter permeaseQuickGO ontologyBLASTP
857259857828570periplasmic binding proteinQuickGO ontologyBLASTP
858764858913150hypothetical proteinBLASTP
858999859274276ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
859365859673309hypothetical proteinBLASTP
859687860232546permeaseQuickGO ontologyBLASTP
860219861025807hypothetical proteinBLASTP
861802862083282hypothetical proteinBLASTP
8622588643632106excinuclease ABC subunit BQuickGO ontologyBLASTP
864557865546990TerC family integral membrane proteinQuickGO ontologyBLASTP
865555866211657Zn-dependent hydrolaseQuickGO ontologyBLASTP
866257867000744mycothiol-dependent maleylpyruvate isomeraseQuickGO ontologyBLASTP
8671518701112961excinuclease ABC subunit AQuickGO ontologyBLASTP