Pre_GI Gene

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Host: NC_016516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016516:1345840 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
134584013470301191D-3-phosphoglycerate dehydrogenaseQuickGO ontologyBLASTP
13470771347862786dipeptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
13478621348671810ATP-binding ABC transporter proteinQuickGO ontologyBLASTP
13486711349483813permease of oligopeptide ABC transporterQuickGO ontologyBLASTP
13494801350457978ABC transporter permeaseQuickGO ontologyBLASTP
135045413519411488ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
13521701352496327XRE family transcriptional regulatorQuickGO ontologyBLASTP
13545671354980414hypothetical proteinBLASTP
13551811355438258hypothetical proteinBLASTP
13554351356019585plasmid partition protein ParAQuickGO ontologyBLASTP
13563931357214822hypothetical proteinBLASTP
13576271357866240hypothetical proteinBLASTP
13585141359236723hypothetical proteinBLASTP
136032413616311308biotin carboxylaseQuickGO ontologyBLASTP
13616181362331714thioesteraseQuickGO ontologyBLASTP
136232813637791452non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
136409013654181329surfactin synthetase subunit 1QuickGO ontologyBLASTP
13659711366261291hypothetical proteinBLASTP
13673941368383990cysteine synthaseornithine cyclodeaminaseQuickGO ontologyBLASTP
13683841369334951cystathionine beta-synthaseQuickGO ontologyBLASTP