Pre_GI Gene

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Host: NC_016512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016512:1357225 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
13572251358037813permease of oligopeptide ABC transporterQuickGO ontologyBLASTP
13580341359011978ABC transporter permeaseQuickGO ontologyBLASTP
135900813604951488ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
13607241360972249XRE family transcriptional regulatorQuickGO ontologyBLASTP
13631221363535414hypothetical proteinBLASTP
13637361363993258hypothetical proteinBLASTP
13639901364574585plasmid partition protein ParAQuickGO ontologyBLASTP
13649481365769822hypothetical proteinBLASTP
13659291366141213hypothetical protein
13661821366421240hypothetical proteinBLASTP
13670691367791723hypothetical proteinBLASTP
136887913701861308biotin carboxylaseQuickGO ontologyBLASTP
13701731370886714thioesteraseQuickGO ontologyBLASTP
137088313726221740non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
137264513737541110surfactin synthetase subunit 1QuickGO ontologyBLASTP
13745741374816243hypothetical proteinBLASTP
13759491376938990cysteine synthaseornithine cyclodeaminaseQuickGO ontologyBLASTP
137693913779401002cystathionine beta-synthaseQuickGO ontologyBLASTP