Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:844500 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
844561846057149730S ribosomal protein S1QuickGO ontologyBLASTP
8462788476811404HtaAQuickGO ontologyBLASTP
8478038489061104hemin receptorQuickGO ontologyBLASTP
8489038499641062Heme ABC transporter permease protein HmuUQuickGO ontologyBLASTP
849961850740780Heme ABC transporter ATPase component HmuVQuickGO ontologyBLASTP
8507438524731731ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8529578541411185ABC-type transport system fused ATPase and permeaseQuickGO ontologyBLASTP
854170854877708dephospho-CoA kinaseQuickGO ontologyBLASTP
8556968569671272htaaQuickGO ontologyBLASTP
857427858248822magnesium chelatase subunit ChlIQuickGO ontologyBLASTP
8584098602111803ATPase family associated with various cellular activities AAAQuickGO ontologyBLASTP
860211860624414hypothetical proteinBLASTP
8607808646133834CobNmagnesium chelatase domain proteinQuickGO ontologyBLASTP
864610865419810ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8654218664641044iron chelate uptake ABC transporter permeaseQuickGO ontologyBLASTP
866461867030570periplasmic binding proteinQuickGO ontologyBLASTP
867966868115150hypothetical proteinBLASTP
868201868476276ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
868567868875309hypothetical proteinBLASTP
868889869434546permeaseQuickGO ontologyBLASTP
869421870218798hypothetical proteinBLASTP
871004871285282hypothetical proteinBLASTP
8714608735652106excinuclease ABC subunit BQuickGO ontologyBLASTP
873759874748990TerC family integral membrane proteinQuickGO ontologyBLASTP
874757875413657Zn-dependent hydrolaseQuickGO ontologyBLASTP