Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:308244 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3082443092571014hypothetical proteinBLASTP
309368309922555inorganic pyrophosphataseQuickGO ontologyBLASTP
3100493114221374D-alanyl-D-alanine carboxypeptidaseD-alanyl-D-alanine-endopeptidaseQuickGO ontologyBLASTP
311422312357936hypothetical proteinBLASTP
312385312939555hypoxanthine phosphoribosyltransferaseQuickGO ontologyBLASTP
3130813152342154cell division protein FtsHQuickGO ontologyBLASTP
315305315874570GTP cyclohydrolase IQuickGO ontologyBLASTP
315947316240294hypothetical proteinBLASTP
3164823175881107OmpA family proteinQuickGO ontologyBLASTP
317588318226639hypothetical proteinBLASTP
318430318954525hypothetical proteinBLASTP
319626320600975hypothetical proteinBLASTP
320743321159417hypothetical proteinBLASTP
321215322060846dihydropteroate synthaseQuickGO ontologyBLASTP
322121322483363dihydroneopterin aldolaseQuickGO ontologyBLASTP
3224803230375582-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinaseQuickGO ontologyBLASTP
323034323570537hypothetical proteinBLASTP
323665324330666hypothetical proteinBLASTP
3244073255971191NADH dehydrogenaseQuickGO ontologyBLASTP
325736326053318hypothetical proteinBLASTP