Pre_GI Gene

Some Help

Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:2389273 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
238927323913422070NAD synthetaseQuickGO ontologyBLASTP
2391521239376722476-phosphofructokinaseQuickGO ontologyBLASTP
239383423949461113alanine dehydrogenaseQuickGO ontologyBLASTP
239524223967321491D-serineD-alanineglycine transporterQuickGO ontologyBLASTP
23976822397813132hypothetical proteinBLASTP
239803723992481212ErfKYbiSYcfSYnhG proteinQuickGO ontologyBLASTP
239951924009851467lipoproteinQuickGO ontologyBLASTP
240128024025661287citrate Si-synthaseQuickGO ontologyBLASTP
240282324038301008adenosine deaminaseQuickGO ontologyBLASTP
240387724049891113alanine dehydrogenaseQuickGO ontologyBLASTP
240516324061701008AsnC family transcriptional regulatorQuickGO ontologyBLASTP
240646424075071044dihydrodipicolinate reductaseQuickGO ontologyBLASTP
24075192407866348hypothetical proteinBLASTP
240786324092841422threonine synthase cystathionine beta-synthaseQuickGO ontologyBLASTP
24092842409706423hypothetical proteinBLASTP
240970324120212319D-ornithine aminomutase E componentQuickGO ontologyBLASTP