Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:1354949 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
135494913561391191D-3-phosphoglycerate dehydrogenaseQuickGO ontologyBLASTP
13561861356971786dipeptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
13569711357780810ATP-binding ABC transporter proteinQuickGO ontologyBLASTP
13577801358592813permease of oligopeptide ABC transporterQuickGO ontologyBLASTP
13585891359566978ABC transporter permeaseQuickGO ontologyBLASTP
135956313610501488ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
13612791361551273XRE family transcriptional regulatorQuickGO ontologyBLASTP
13636771364090414hypothetical proteinBLASTP
13642911364548258hypothetical proteinBLASTP
13645451365129585plasmid partition protein ParAQuickGO ontologyBLASTP
13655031366324822hypothetical proteinBLASTP
13667371366976240hypothetical proteinBLASTP
13676241368346723hypothetical proteinBLASTP
136943413707411308biotin carboxylaseQuickGO ontologyBLASTP
13707281371441714thioesteraseQuickGO ontologyBLASTP
137143813728891452non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
137320013745281329surfactin synthetase subunit 1QuickGO ontologyBLASTP
13750811375371291hypothetical proteinBLASTP
13765041377493990cysteine synthaseornithine cyclodeaminaseQuickGO ontologyBLASTP
13774941378444951cystathionine beta-synthaseQuickGO ontologyBLASTP