Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:290355 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2903552921031749phosphomannomutaseQuickGO ontologyBLASTP
2923622934471086transposase in ISPg1QuickGO ontologyBLASTP
293468293572105hypothetical protein
2948572959421086transposase in ISPg1QuickGO ontologyBLASTP
297805298173369hypothetical protein
300641300904264CRISPR-associated Cas2 family proteinQuickGO ontologyBLASTP
3009043019201017CRISPR-associated Cas1 family proteinQuickGO ontologyBLASTP
301917302348432CRISPR-associated Cas4 family proteinQuickGO ontologyBLASTP
3024493047522304CRISPR-associated helicase Cas3QuickGO ontologyBLASTP
3047423057581017hypothetical proteinBLASTP
3057693072681500hypothetical proteinBLASTP
307265308008744hypothetical proteinBLASTP
308005308670666CRISPR-associated Cas5e family proteinQuickGO ontologyBLASTP
308745308984240hypothetical proteinBLASTP
3093173112481932putative sulfataseQuickGO ontologyBLASTP
3112523137952544hypothetical proteinBLASTP
313960314931972methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP