Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:2273503 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
22735032274045543histone-like family DNA-binding proteinQuickGO ontologyBLASTP
22740682274283216hypothetical proteinBLASTP
22745812275147567elongation factor PQuickGO ontologyBLASTP
22752032275358156hypothetical proteinBLASTP
227559722768261230ornithine aminotransferaseQuickGO ontologyBLASTP
22768332277762930putative amidinotransferaseQuickGO ontologyBLASTP
227783922794701632delta-1-pyrroline-5-carboxylate dehydrogenaseQuickGO ontologyBLASTP
22796972279987291hypothetical proteinBLASTP
22800532280238186hypothetical proteinBLASTP
22802822281801152016S ribosomal RNAQuickGO ontologyBLASTP
22818582282019162hypothetical proteinBLASTP
2282303228237674tRNA-IleQuickGO ontologyBLASTP
2282378228245477tRNA-AlaQuickGO ontology
22825632285459289723S ribosomal RNAQuickGO ontologyBLASTP
228555422856631105S ribosomal RNAQuickGO ontologyBLASTP
228586822890923225UvrDREP helicase domain-containing proteinQuickGO ontologyBLASTP
22890892289949861hypothetical proteinBLASTP
22899942290920927hypothetical proteinBLASTP
22909322291663732short chain dehydrogenasereductase family oxidoreductaseQuickGO ontologyBLASTP
22916692292127459glycerol-3-phosphate cytidylyltransferaseQuickGO ontologyBLASTP
229214922932461098pyridoxal phosphate biosynthetic protein PdxAQuickGO ontologyBLASTP