Pre_GI Gene

Some Help

Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:2002489 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
200248920099887500gliding motility protein SprAQuickGO ontologyBLASTP
20100282010636609Holliday junction DNA helicase RuvAQuickGO ontologyBLASTP
20120402012246207hypothetical proteinBLASTP
201302620141111086transposase in ISPg1QuickGO ontologyBLASTP
20140752014182108hypothetical proteinBLASTP
2014854201494188tRNA-SerQuickGO ontologyBLASTP
201502920173652337putative RloC proteinQuickGO ontologyBLASTP
201744020188821443hypothetical proteinBLASTP
201887620202491374putative type I restriction-modification system M subunitQuickGO ontologyBLASTP
20202582020908651putative type I restriction-modification system M subunitQuickGO ontologyBLASTP
20214302021702273hypothetical proteinBLASTP
202169920227631065mobilizable transposon proteinQuickGO ontologyBLASTP
20229062023853948CHC2 zinc finger containing proteinQuickGO ontologyBLASTP
20239562024303348mobilization proteinQuickGO ontologyBLASTP
20243002025226927mobilization proteinQuickGO ontologyBLASTP
20252482025907660hypothetical proteinBLASTP
202604520270761032hypothetical protein
202723120284991269hypothetical proteinBLASTP
202851120298091299integraseQuickGO ontologyBLASTP
203029020315821293integraseQuickGO ontologyBLASTP
20315792032034456hypothetical proteinBLASTP
20320272032254228hypothetical protein
20324722032714243hypothetical protein
20327452033014270excisionase family DNA binding proteinQuickGO ontologyBLASTP
20330352033340306excisionase family DNA binding proteinQuickGO ontologyBLASTP
20333372033813477hypothetical proteinBLASTP
20337982033998201hypothetical protein
20340052034430426hypothetical proteinBLASTP
20344202035223804hypothetical proteinBLASTP
203515620365861431type I restriction-modification systemQuickGO ontologyBLASTP
203658120381431563type I restriction-modification system subunit SQuickGO ontologyBLASTP
20381402038619480death-on-curing family proteinQuickGO ontologyBLASTP
203861220396281017putative DNA-binding proteinQuickGO ontologyBLASTP
203964020411481509type I restriction-modification system subunit MQuickGO ontologyBLASTP