Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:168617 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1686171696511035tRNA 2-selenouridine synthaseQuickGO ontologyBLASTP
169648170262615hypothetical proteinBLASTP
170403171065663hypothetical proteinBLASTP
171178171279102hypothetical protein
171328171504177hypothetical protein
171654172091438putative lipoproteinQuickGO ontologyBLASTP
1721271784506324hypothetical proteinBLASTP
178455178904450hypothetical proteinBLASTP
179039179452414hypothetical proteinBLASTP
179466179942477hypothetical proteinBLASTP
1799901813901401putative integrin subunit alphaQuickGO ontologyBLASTP
181403181858456hypothetical proteinBLASTP
182677183072396hypothetical proteinBLASTP
183367183762396hypothetical proteinBLASTP
184011184487477hypothetical proteinBLASTP
184533185162630hypothetical proteinBLASTP
185168185857690hypothetical proteinBLASTP
185940186482543hypothetical proteinBLASTP
186500186910411hypothetical proteinBLASTP
1872011884901290S-adenosylmethionine synthetaseQuickGO ontologyBLASTP
188619189296678thiamin pyrophosphokinase catalytic subunitQuickGO ontologyBLASTP
189293189901609transporterQuickGO ontologyBLASTP
1899061922902385TonB-dependent receptorQuickGO ontologyBLASTP
192366193313948ribosome-associated GTPaseQuickGO ontologyBLASTP
193398193958561ribosome recycling factorQuickGO ontologyBLASTP
193995194714720uridylate kinaseQuickGO ontologyBLASTP
1947971967881992hypothetical proteinBLASTP
197020197304285hypothetical proteinBLASTP