Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:1495286 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
14952861495615330hypothetical proteinBLASTP
149588014973731494histidine ammonia-lyaseQuickGO ontologyBLASTP
14973761498005630putative methenyltetrahydrofolate cyclohydrolaseQuickGO ontologyBLASTP
149803014991781149hypothetical proteinBLASTP
149926215004161155hypothetical proteinBLASTP
150051015017811272imidazolonepropionaseQuickGO ontologyBLASTP
15018821502766885formiminotransferase-cyclodeaminaseQuickGO ontologyBLASTP
15028251503790966hypothetical proteinBLASTP
15038531504371519piutative DNA-binding protein histone-likefamilyQuickGO ontologyBLASTP
150504715070231977transcription termination factor RhoQuickGO ontologyBLASTP
15072511508159909hypothetical proteinBLASTP
15081701509129960glycosyl transferase group 2 family proteinQuickGO ontologyBLASTP
15091821510084903tRNA delta2-isopentenylpyrophosphate transferaseQuickGO ontologyBLASTP
15101011510670570hypothetical proteinBLASTP
15107551510898144hypothetical proteinBLASTP
151095815143173360hypothetical proteinBLASTP
15143221514867546hypothetical proteinBLASTP