Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:1265121 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
12645011265124624recombination protein RecRQuickGO ontologyBLASTP
126512112666351515putative ribonuclease EQuickGO ontologyBLASTP
12669571267235279DNA-binding protein HUQuickGO ontologyBLASTP
12673471267838492anaerobic ribonucleoside-triphosphate reductase activating proteinQuickGO ontologyBLASTP
126787112702672397anaerobic ribonucleoside triphosphate reductaseQuickGO ontologyBLASTP
127066512716931029transposase in ISPg2QuickGO ontologyBLASTP
12720101272477468transposase in ISPg3QuickGO ontologyBLASTP
12729461273086141hypothetical proteinBLASTP
127364712737561105S ribosomal RNAQuickGO ontologyBLASTP
12738511276747289723S ribosomal RNAQuickGO ontologyBLASTP
1276856127693277tRNA-AlaQuickGO ontology
1276934127700774tRNA-IleQuickGO ontologyBLASTP
12772911277452162hypothetical proteinBLASTP
12775101279031152216S ribosomal RNAQuickGO ontologyBLASTP
12790751279377303hypothetical proteinBLASTP
12793761279702327hypothetical proteinBLASTP
12799261280147222hypothetical proteinBLASTP
128021412813861173hypothetical proteinBLASTP
128185112832061356Na-translocating NADH-quinone reductase subunit AQuickGO ontologyBLASTP
128323712844361200Na-translocating NADH-quinone reductase subunit BQuickGO ontologyBLASTP
12844601285194735Na-translocating NADH-quinone reductase subunit CQuickGO ontologyBLASTP
12852001285829630Na-translocating NADH-quinone reductase subunit DQuickGO ontologyBLASTP
12858691286483615Na-translocating NADH-quinone reductase subunit EQuickGO ontologyBLASTP
128650212877401239Na-translocating NADH-quinone reductase subunit FQuickGO ontologyBLASTP
1288072128814675tRNA-MetQuickGO ontology