Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:1065775 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10657751066695921conjugative transposon protein TraNQuickGO ontologyBLASTP
10666971067281585conjugative transposon protein TraOQuickGO ontologyBLASTP
10672811068126846mobilizable transposon excision proteinQuickGO ontologyBLASTP
10681541068615462conjugative transposon protein TraQQuickGO ontologyBLASTP
10688211069114294putative lysozymeQuickGO ontologyBLASTP
10692301069799570hypothetical protein
10698251069929105hypothetical protein
10699661070202237hypothetical proteinBLASTP
107021210714861275hypothetical proteinBLASTP
10715041072034531putative anti-restriction proteinQuickGO ontologyBLASTP
10720531072466414hypothetical proteinBLASTP
10724841073074591hypothetical proteinBLASTP
10730871073368282hypothetical proteinBLASTP
10733801073598219hypothetical proteinBLASTP
10736111073820210hypothetical protein
10739931074226234hypothetical protein
10745331075405873SerB family proteinQuickGO ontologyBLASTP
107562110767211101hypothetical protein
10772511078006756hypothetical proteinBLASTP
10782431078824582hypothetical proteinBLASTP
10791101079229120hypothetical protein
10797171079848132hypothetical protein
10799871080577591xanthosine triphosphate pyrophosphataseQuickGO ontologyBLASTP
10805791081007429hypothetical protein
10810121081713702hypothetical protein
108172610830421317hypothetical protein
108304210843371296metal-dependent hydrolaseQuickGO ontologyBLASTP
10848491084992144hypothetical protein
108524910865681320cobyrinic acid ac-diamide synthaseQuickGO ontologyBLASTP