Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4969549 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
49695494970391843ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
497057349715801008transcriptional regulatorQuickGO ontologyBLASTP
497170949727281020stage II sporulation protein DQuickGO ontologyBLASTP
497293749742411305UDP-N-acetylglucosamine 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
49742814974991711hypothetical proteinBLASTP
49750374975273237hypothetical proteinBLASTP
497548649770061521NADH dehydrogenase subunit NQuickGO ontologyBLASTP
497700849785101503NADH dehydrogenase subunit MQuickGO ontologyBLASTP
497850749803691863NADH dehydrogenase subunit LQuickGO ontologyBLASTP
49803994980713315NADH dehydrogenase kappa subunitQuickGO ontologyBLASTP
49807064981230525NADH dehydrogenase subunit JQuickGO ontologyBLASTP
49812274981646420NADH dehydrogenase subunit IQuickGO ontologyBLASTP
498167249826731002NADH dehydrogenase subunit HQuickGO ontologyBLASTP
498267349837731101NADH dehydrogenase delta subunitQuickGO ontologyBLASTP
498377849850431266NADH dehydrogenase I subunit CQuickGO ontologyBLASTP
49850404985558519NADH dehydrogenase subunit betaQuickGO ontologyBLASTP
49855494985917369NADH dehydrogenase subunit alphaQuickGO ontologyBLASTP
498620849889372730sensory boxGGDEF family proteinQuickGO ontologyBLASTP
49890104989663654hypothetical proteinBLASTP
49897114990502792hypothetical proteinBLASTP
49906364991037402ATP synthase subunit EQuickGO ontologyBLASTP
499105849924671410ATP synthase subunit BQuickGO ontologyBLASTP