Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4848389 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
48483894848748360hypothetical proteinBLASTP
48488544849165312hypothetical proteinBLASTP
484923148509461716multidrug resistance ABC transporter ATP-binding proteinpermeaseQuickGO ontologyBLASTP
485126148524451185membrane proteinQuickGO ontologyBLASTP
485255548539911437carboxyl-terminal proteaseQuickGO ontologyBLASTP
48541104855003894cell division ABC transporter permeaseQuickGO ontologyBLASTP
48549934855679687cell division ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
48559664856289324cytochrome c-551QuickGO ontologyBLASTP
48565444856726183hypothetical proteinBLASTP
48567264857706981peptide chain release factor 2QuickGO ontologyBLASTP
485796948604762508translocaseQuickGO ontologyBLASTP
48607534861295543ribosomal subunit interface proteinQuickGO ontologyBLASTP
48616224861825204cold shock proteinQuickGO ontologyBLASTP
48619464862650705ComF operon protein 3QuickGO ontologyBLASTP
486265048639991350ComF operon protein 1QuickGO ontologyBLASTP
486412748656441518NLPP60 family proteinQuickGO ontologyBLASTP
48656954866009315putative transcriptional regulatorQuickGO ontologyBLASTP
48661834867025843DegV family proteinQuickGO ontologyBLASTP
48672654867900636hypothetical proteinBLASTP
486797548691021128LytR family transcription antiterminatorQuickGO ontologyBLASTP
486913848702531116UDP-N-acetylglucosamine 2-epimeraseQuickGO ontologyBLASTP
487032848716981371UDP-glucose 6-dehydrogenaseQuickGO ontologyBLASTP
487218848732611074glycosyl transferase group 4 family proteinQuickGO ontologyBLASTP