Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4800500 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
48012834801657375hypothetical proteinBLASTP
48023084802775468SsrA-binding proteinQuickGO ontologyBLASTP
480311148055312421ribonuclease RQuickGO ontologyBLASTP
48056744806417744carboxylesteraseQuickGO ontologyBLASTP
48065764806809234membrane proteinQuickGO ontologyBLASTP
48069044807596693putative murein hydrolase export regulatorQuickGO ontologyBLASTP
48075934807967375putative murein hydrolase exporter LrgA familyQuickGO ontologyBLASTP
48083874809337951inosine-uridine preferring nucleoside hydrolaseQuickGO ontologyBLASTP
480938848106831296enolaseQuickGO ontologyBLASTP
481071448122431530phosphoglyceromutaseQuickGO ontologyBLASTP
48122404812995756triosephosphate isomeraseQuickGO ontologyBLASTP
481302848142121185phosphoglycerate kinaseQuickGO ontologyBLASTP
481435248153561005glyceraldehyde-3-phosphate dehydrogenaseQuickGO ontologyBLASTP
481538348164111029central glycolytic genes regulatorQuickGO ontologyBLASTP
48165474816792246glutaredoxin family proteinQuickGO ontologyBLASTP
481680248181091308DNA-directed RNA polymerase subunit NQuickGO ontologyBLASTP