Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4697293 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46972934697679387lipoproteinQuickGO ontologyBLASTP
46982114698534324hypothetical proteinBLASTP
46985314699058528lipoproteinQuickGO ontologyBLASTP
46992024699849648hypothetical proteinBLASTP
469990747009201014hypothetical proteinBLASTP
470094347020461104L-lactate dehydrogenaseQuickGO ontologyBLASTP
47021404702388249spore coat protein F-related proteinQuickGO ontologyBLASTP
47024024702587186hypothetical proteinBLASTP
47027904703032243hypothetical protein
47033924703940549putative TetR family transcriptional regulatorQuickGO ontologyBLASTP
47039444704666723metallo-beta-lactamase family proteinQuickGO ontologyBLASTP
470480647065901785acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
470690947080811173acetyl-CoA acetyltransferaseQuickGO ontologyBLASTP
470810347104842382bifunctional 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratasecarnithine racemaseQuickGO ontologyBLASTP
47107204710866147hypothetical proteinBLASTP
47109544711793840serine-type D-Ala-D-Ala carboxypeptidaseQuickGO ontologyBLASTP
47118164712733918proline dehydrogenaseQuickGO ontologyBLASTP
47130454713290246hypothetical proteinBLASTP
47133394713641303hypothetical proteinBLASTP
471371947157282010methyl-accepting chemotaxis proteinQuickGO ontologyBLASTP