Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4622500 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46225084622975468hypothetical proteinBLASTP
46230934623806714hypothetical proteinBLASTP
462415446255301377glycyl-tRNA synthetaseQuickGO ontologyBLASTP
46255684625951384thioesterase superfamily proteinQuickGO ontologyBLASTP
46260474626790744hypothetical proteinBLASTP
46268414627434594biotin synthesis BioY proteinQuickGO ontologyBLASTP
46274804628367888UTP-glucose-1-phosphate uridylyltransferaseQuickGO ontologyBLASTP
462847646302001725phosphoglucomutasephosphomannomutase family proteinQuickGO ontologyBLASTP
46303444630949606hypothetical proteinBLASTP
463103246325161485putative cytosol aminopeptidaseQuickGO ontologyBLASTP
463266346333226603D domain-containing proteinQuickGO ontologyBLASTP
46333764633693318hypothetical proteinBLASTP
46336904634196507MutTNudix family proteinQuickGO ontologyBLASTP
463432046355311212pyridine nucleotide-disulfide oxidoreductaseQuickGO ontologyBLASTP
46359914636980990thioredoxin-disulfide reductaseQuickGO ontologyBLASTP
463709946452738175putative cell surface proteinQuickGO ontologyBLASTP