Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4442500 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
44426204442898279hypothetical proteinBLASTP
44429334443115183hypothetical proteinBLASTP
44431174443353237hypothetical proteinBLASTP
44436244444103480CarD-like transcriptional regulatorQuickGO ontologyBLASTP
44441764444961786glucose-1-dehydrogenaseQuickGO ontologyBLASTP
44449754445832858glucose uptake proteinQuickGO ontologyBLASTP
44458694446288420hypothetical proteinBLASTP
44463824446615234molybdopterin converting factor subunit 1QuickGO ontologyBLASTP
44466184447082465molybdopterin converting factor large subunitQuickGO ontologyBLASTP
444723744483641128putative transposaseQuickGO ontologyBLASTP
44485584449076519molybdopterin-guanine dinucleotide biosynthesis protein BQuickGO ontologyBLASTP
444904644503351290molybdopterin biosynthesis proteinQuickGO ontologyBLASTP
44504194450904486molybdenum cofactor biosynthesis protein CQuickGO ontologyBLASTP
445094344519561014molybdopterin biosynthesis protein MoeBQuickGO ontologyBLASTP
445197344529861014molybdenum cofactor biosynthesis protein AQuickGO ontologyBLASTP
445316044557212562collagen triple helix repeat domain-containing proteinQuickGO ontologyBLASTP
44558954456218324hypothetical proteinBLASTP
44562394456463225hypothetical proteinBLASTP
44565414456846306rhodanese-like domain-containing proteinQuickGO ontologyBLASTP
44570474457229183hypothetical proteinBLASTP
445727944584031125homoserine O-acetyltransferaseQuickGO ontologyBLASTP
445855644604721917spore germination protein GerHAQuickGO ontologyBLASTP