Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4113154 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
411315441138496965-methylthioadenosineS-adenosylhomocysteine nucleosidaseQuickGO ontologyBLASTP
41138644114502639hypothetical proteinBLASTP
41146394114854216hypothetical proteinBLASTP
41148904115540651hypothetical proteinBLASTP
411565741174111755penicillin-binding proteinQuickGO ontologyBLASTP
41175044118031528transcription elongation factorQuickGO ontologyBLASTP
41182594118897639uridine kinaseQuickGO ontologyBLASTP
411891541201951281U32 family peptidaseQuickGO ontologyBLASTP
41202144121143930U32 family peptidaseQuickGO ontologyBLASTP
41211514121792642O-methyltransferase family proteinQuickGO ontologyBLASTP
412199541230651071aminodeoxychorismate lyaseQuickGO ontologyBLASTP
41232834123561279hypothetical proteinBLASTP
41235744123987414holliday junction resolvase-like proteinQuickGO ontologyBLASTP
41239914124257267hypothetical proteinBLASTP
412433441269762643alanyl-tRNA synthetaseQuickGO ontologyBLASTP
41274594127803345hypothetical proteinBLASTP
412784241289091068membrane proteinQuickGO ontologyBLASTP
41290984129310213hypothetical proteinBLASTP
41294964129684189hypothetical proteinBLASTP
412981241321482337RecDTraA family helicaseQuickGO ontologyBLASTP