Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:3902155 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
39021553902589435MerR family transcriptional regulatorQuickGO ontologyBLASTP
39027123903170459MutTNudix family proteinQuickGO ontologyBLASTP
390333739045151179FtsWRodASpoVE family cell division proteinQuickGO ontologyBLASTP
390485739061761320dihydrolipoamide acetyltransferaseQuickGO ontologyBLASTP
390619239071759843-methyl-2-oxobutanoate dehydrogenase subunit betaQuickGO ontologyBLASTP
3907189390819010023-methyl-2-oxobutanoate dehydrogenase subunit alphaQuickGO ontologyBLASTP
390821839096391422dihydrolipoamide dehydrogenaseQuickGO ontologyBLASTP
390964439107741131butyrate kinaseQuickGO ontologyBLASTP
391083539119351101leucine dehydrogenaseQuickGO ontologyBLASTP
39119703912869900phosphate acetyltransferaseQuickGO ontologyBLASTP
391306539151372073sensory box sigma-54 dependent DNA-binding response regulatorQuickGO ontologyBLASTP
39152743915507234metallo-beta-lactamase family proteinQuickGO ontologyBLASTP
39155563916284729glycerophosphoryl diester phosphodiesteraseQuickGO ontologyBLASTP
39163353916481147ferrichrome transporter permease fhuBQuickGO ontologyBLASTP
391664939181751527hemagglutininQuickGO ontologyBLASTP
39184613919291831stage 0 sporulation protein AQuickGO ontologyBLASTP
39193833919535153pullulanaseQuickGO ontologyBLASTP
391954339208411299stage IV sporulation protein BQuickGO ontologyBLASTP