Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:3408081 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
340808134095981518histidine ammonia-lyaseQuickGO ontologyBLASTP
34097043410144441anti-terminator HutPQuickGO ontologyBLASTP
34103403410801462hypothetical proteinBLASTP
34107083411163456putative proteaseQuickGO ontologyBLASTP
34111603411738579hypothetical proteinBLASTP
34119933412289297hypothetical proteinBLASTP
34123933412833441hypothetical proteinBLASTP
341286334139181056hypothetical proteinBLASTP
341419634217587563hypothetical proteinBLASTP
34218213422327507cyotchrome c defective proteinQuickGO ontologyBLASTP
34224183423125708cytochrome c-type biogenesis proteinQuickGO ontologyBLASTP
34236123424520909hypothetical proteinBLASTP
342460834257531146N-acyl-L-amino acid amidohydrolaseQuickGO ontologyBLASTP
34257913426735945bacitracin transport permeaseQuickGO ontologyBLASTP
34267283427639912C-terminal part of bacitracin transport ATP-binding protein BcrAQuickGO ontologyBLASTP
34277303427924195N-terminal part of bacitracin transport ATP-binding protein BcrAQuickGO ontologyBLASTP
34285373429442906LysR family transcriptional regulatorQuickGO ontologyBLASTP
34295953429960366LrgA family proteinQuickGO ontologyBLASTP
34299573430634678LrgB family proteinQuickGO ontologyBLASTP
34306473430784138C-terminal part of NUDIX hydrolaseQuickGO ontologyBLASTP
34307813431059279N-terminal part of NUDIX hydrolaseQuickGO ontologyBLASTP
34312013431401201hypothetical proteinBLASTP
34317173432520804membrane proteinQuickGO ontologyBLASTP
34325813432727147hypothetical proteinBLASTP