Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:2718000 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
27181742719022849hypothetical proteinBLASTP
271935727224733117membrane proteinQuickGO ontologyBLASTP
27227272723293567TetR family transcriptional regulatorQuickGO ontologyBLASTP
272358327247401158acetyltransferase GNAT familyQuickGO ontologyBLASTP
2725029272631812903-phosphoshikimate 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
272633527274441110prephenate dehydrogenaseQuickGO ontologyBLASTP
272742827285281101putative aminotransferaseQuickGO ontologyBLASTP
272854727297191173chorismate synthaseQuickGO ontologyBLASTP
2730002273107810773-deoxy-7-phosphoheptulonate synthaseQuickGO ontologyBLASTP
273191027353923483hypothetical proteinBLASTP
27355742736011438hypothetical proteinBLASTP
27361812736711531isochorismataseQuickGO ontologyBLASTP
27367282737261534acetyltransferase GNAT familyQuickGO ontologyBLASTP
27372752737580306hypothetical proteinBLASTP
27376792738197519hypothetical proteinBLASTP
273824927397631515putative enterotoxinQuickGO ontologyBLASTP