Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:2274774 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
22747742275628855hypothetical proteinBLASTP
22755942275863270hypothetical proteinBLASTP
227593722773011365ATP-dependent RNA helicaseQuickGO ontologyBLASTP
22775942277743150hypothetical proteinBLASTP
22786272279130504hypothetical proteinBLASTP
22796142279790177hypothetical protein
22799002280316417TetR family transcriptional regulatorQuickGO ontologyBLASTP
22825972283445849hypothetical proteinBLASTP
22837612284249489hypothetical proteinBLASTP
22849082285102195hypothetical protein
22852062285496291hypothetical protein
22856442286522879hypothetical proteinBLASTP
22865922287071480hypothetical proteinBLASTP
22870712287505435hypothetical proteinBLASTP
22880842288419336hypothetical protein
22885202288801282hypothetical protein
22886982288835138hypothetical protein
22891832289722540hypothetical protein
22898212290603783hypothetical proteinBLASTP
22907522291705954DNA integrationrecombinationinvertion proteinQuickGO ontologyBLASTP
22918062292006201TetR family transcriptional regulatorQuickGO ontologyBLASTP
229206922933161248putative ABC transporter permeaseQuickGO ontologyBLASTP
229345422956612208ABC transporter permeaseQuickGO ontologyBLASTP
22956642296434771ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
22965332297243711methyltransferaseQuickGO ontologyBLASTP
22973632297770408putative 3-demethylubiquinone-9 3-methyltransferaseQuickGO ontologyBLASTP
22980562298838783methyltransferaseQuickGO ontologyBLASTP
22999392300787849DNA integrationrecombinationinvertion proteinQuickGO ontologyBLASTP
23014172301671255hypothetical protein
23017622302103342hypothetical proteinBLASTP