Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:2009662 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
200966220123372676TPR repeat-containing proteinQuickGO ontologyBLASTP
20123612013089729hypothetical proteinBLASTP
201325920150611803hypothetical proteinBLASTP
20151322015569438hypothetical proteinBLASTP
201562620170411416hypothetical proteinBLASTP
20170572017413357hypothetical proteinBLASTP
20181032018888786DNA integrationrecombinationinvertion proteinQuickGO ontologyBLASTP
20205342020815282hypothetical proteinBLASTP
20208292021527699hypothetical proteinBLASTP
20219562022648693transposaseQuickGO ontologyBLASTP
20226542023142489hypothetical proteinBLASTP
20240182024317300hypothetical proteinBLASTP
20245162025133618hypothetical proteinBLASTP
20258092026090282hypothetical proteinBLASTP
20261182026654537hypothetical proteinBLASTP
20266712026994324hypothetical proteinBLASTP
20270182027674657hypothetical protein
20277552028240486hypothetical proteinBLASTP
20282672028623357hypothetical proteinBLASTP
202914220303261185glycerate kinaseQuickGO ontologyBLASTP
203032320317531431sodiumsolute symporter family proteinQuickGO ontologyBLASTP
20318822032565684DNA-binding response regulatorQuickGO ontologyBLASTP