Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:1094000 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
109404210956311590malate synthaseQuickGO ontologyBLASTP
109565510969321278isocitrate lyaseQuickGO ontologyBLASTP
10971061097897792trifolitoxin immunity proteinQuickGO ontologyBLASTP
10982491098452204cold shock proteinQuickGO ontologyBLASTP
10986411098853213hypothetical proteinBLASTP
10991381099323186hypothetical proteinBLASTP
10996051100186582competence transcription factorQuickGO ontologyBLASTP
11004601101053594membrane proteinQuickGO ontologyBLASTP
11011101101673564signal peptidase IQuickGO ontologyBLASTP
110179011053053516ATP-dependent nuclease subunit BQuickGO ontologyBLASTP
110530211090273726ATP-dependent nuclease subunit AQuickGO ontologyBLASTP
11090401109327288hypothetical proteinBLASTP
11093651110180816IS660 transposaseQuickGO ontologyBLASTP
11102541110826573IS660 transposaseQuickGO ontologyBLASTP
11109551111170216spore germination protein PFQuickGO ontologyBLASTP
11112131111599387spore germination protein PEQuickGO ontologyBLASTP
11116151111809195spore germination protein PDQuickGO ontologyBLASTP
11118161112430615spore germination protein PCQuickGO ontologyBLASTP
11124981112704207spore germination protein PBQuickGO ontologyBLASTP
11127191112940222spore germination protein PAQuickGO ontologyBLASTP
11130371113216180putative stage 0 sporulation regulatory proteinQuickGO ontologyBLASTP
11132161113365150hypothetical protein
11134551114363909fumarylacetoacetate hydrolase family proteinQuickGO ontologyBLASTP
11143991114683285hypothetical proteinBLASTP
111479011159801191ornithine-oxo-acid transaminaseQuickGO ontologyBLASTP