Pre_GI Gene

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Host: NC_014332 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014332:1 Bacillus cereus biovar anthracis str. CI plasmid pCI-XO2, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5114211371hypothetical proteinBLASTP
14402036597hypothetical proteinBLASTP
20482335288hypothetical proteinBLASTP
2549263890hypothetical proteinBLASTP
26433500858hypothetical proteinBLASTP
34973772276hypothetical proteinBLASTP
38614469609hypothetical proteinBLASTP
449456361143putative nlpp60 family proteinQuickGO ontologyBLASTP
563875721935putative hydrolaseQuickGO ontologyBLASTP
75898257669hypothetical proteinBLASTP
83218635315hypothetical proteinBLASTP
86388841204hypothetical proteinBLASTP
88439097255hypothetical proteinBLASTP
9115120722958hypothetical proteinBLASTP
1207212890819hypothetical proteinBLASTP
12911147281818TraGTraF family conjugation proteinQuickGO ontologyBLASTP
14754166791926hypothetical protein