Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:869826 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
869826870602777sortase family proteinQuickGO ontologyBLASTP
870927872423149730S ribosomal protein S1QuickGO ontologyBLASTP
8726118740471437HtaAQuickGO ontologyBLASTP
874228874353126hypothetical protein
874373875272900Heme ABC transporter cell surface heme and hemoprotein receptor HmuTQuickGO ontologyBLASTP
8752698763301062Heme ABC transporter permease protein HmuUQuickGO ontologyBLASTP
876327877106780Heme ABC transporter ATPase component HmuVQuickGO ontologyBLASTP
877109877594486hypothetical proteinBLASTP
8774648787621299ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8789138804331521ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
880475881170696dephospho-CoA kinaseQuickGO ontologyBLASTP
8816038832611659htaaQuickGO ontologyBLASTP
883721884701981magnesium chelatase subunit ChlIQuickGO ontologyBLASTP
8847038865051803ATPase family associated with various cellular activities AAAQuickGO ontologyBLASTP
886505886918414hypothetical proteinBLASTP
8870748909073834CobNmagnesium chelatase domain proteinQuickGO ontologyBLASTP
890904891701798ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8917158927581044iron chelate uptake ABC transporter FeCT family permease proteinQuickGO ontologyBLASTP
8927558937681014periplasmic binding proteinQuickGO ontologyBLASTP
894260894409150hypothetical proteinBLASTP
894861895169309hypothetical proteinBLASTP
895183895419237hypothetical proteinBLASTP
895715896521807hypothetical proteinBLASTP
8977558998602106excinuclease ABC B subunitQuickGO ontologyBLASTP
900054901043990integral membrane protein TerC familyQuickGO ontologyBLASTP
901052901708657metallo-beta-lactamase domain proteinQuickGO ontologyBLASTP
901754902686933hypothetical proteinBLASTP
9026489056082961excinuclease ABC A subunitQuickGO ontologyBLASTP
905623906030408twin-arginine translocated Rieske 2Fe-2S domain proteinQuickGO ontologyBLASTP
906046906792747phosphoglycerate mutase family proteinQuickGO ontologyBLASTP
9069699086181650hypothetical protein