Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:261126 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
261126261626501hypothetical proteinBLASTP
2618372629401104hypothetical proteinBLASTP
2629222643971476YD repeat proteinQuickGO ontologyBLASTP
2644642669922529YD repeat proteinQuickGO ontologyBLASTP
267093267275183hypothetical proteinBLASTP
267262268107846hypothetical proteinBLASTP
268481269380900hypothetical proteinBLASTP
270049270165117hypothetical proteinBLASTP
2713222742342913RHS repeat-associated core domain proteinQuickGO ontologyBLASTP
2741892769812793YD repeat proteinQuickGO ontologyBLASTP
277101277823723hypothetical proteinBLASTP
278193278558366S4 domain proteinQuickGO ontologyBLASTP
278841279197357hypothetical proteinBLASTP
2792652821382874DNA polymerase III subunit gamma and tauQuickGO ontologyBLASTP
282248282571324DNA-binding protein YbaBEbfC familyQuickGO ontologyBLASTP
282602283207606recombination protein RecRQuickGO ontologyBLASTP
283315283890576transcriptional regulator PadR familyQuickGO ontologyBLASTP
283896284678783ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
2846752873172643efflux ABC transporter permease proteinQuickGO ontologyBLASTP