Pre_GI Gene

Some Help

Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:2386347 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
238634723884162070NAD synthetaseQuickGO ontologyBLASTP
2388577239084122656-phosphofructokinaseQuickGO ontologyBLASTP
239090823920291122alanine dehydrogenaseQuickGO ontologyBLASTP
2392078239217699hypothetical protein
239230723938061500D-serineD-alanineglycine transporterQuickGO ontologyBLASTP
23947562394887132hypothetical proteinBLASTP
239511123963221212ErfKYbiSYcfSYnhGQuickGO ontologyBLASTP
239659323980591467lipoprotein A-like proteinQuickGO ontologyBLASTP
239835423996401287citrate Si-synthaseQuickGO ontologyBLASTP
239978624009041119putative adenosine deaminaseQuickGO ontologyBLASTP
240095124020721122alanine dehydrogenaseQuickGO ontologyBLASTP
240223724032441008transcriptional regulator AsnC familyQuickGO ontologyBLASTP
240353824045811044dihydrodipicolinate reductaseQuickGO ontologyBLASTP
24045932404940348hypothetical proteinBLASTP
2404937240635814222-amino-4-ketopentanoate thiolase beta subunitQuickGO ontologyBLASTP
24063582406780423hypothetical proteinBLASTP