Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:1766049 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
17660491766501453hypothetical proteinBLASTP
17664981766632135hypothetical proteinBLASTP
17666331767379747ABC transporter permease proteinQuickGO ontologyBLASTP
17674531768019567hypothetical proteinBLASTP
17681031768588486Thiol peroxidase Bcp-typeQuickGO ontologyBLASTP
1768639176872385tRNA-LeuQuickGO ontologyBLASTP
17691261770004879glycosyl hydrolase family 25QuickGO ontologyBLASTP
17704131770676264hypothetical proteinBLASTP
17711111771440330hypothetical proteinBLASTP
17716001771785186hypothetical proteinBLASTP
177215017734421293thrombospondin type 3 repeat proteinQuickGO ontologyBLASTP
17734611774336876hypothetical proteinBLASTP
17747531775010258hypothetical protein
17751591776049891transcriptional regulator RpiR familyQuickGO ontologyBLASTP
17761001776222123hypothetical protein
17762821776446165hypothetical protein
177640717783201914hypothetical proteinBLASTP
177837317797701398ImpBMucBSamB family proteinQuickGO ontologyBLASTP
17797671780237471dihydrofolate reductaseQuickGO ontologyBLASTP
17802811781093813thymidylate synthaseQuickGO ontologyBLASTP
17810941781708615non-canonical purine NTP pyrophosphatase RdgBHAM1 familyQuickGO ontologyBLASTP
17817051782469765tRNA nucleotidyltransferaseQuickGO ontologyBLASTP
17825031783357855glutamate racemaseQuickGO ontologyBLASTP
17835411783858318FeoA domain proteinQuickGO ontologyBLASTP
178399117858771887ferrous iron transport protein BQuickGO ontologyBLASTP
17858771786419543NifU-like proteinQuickGO ontologyBLASTP