Pre_GI Gene

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Host: NC_012731 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012731:2974745 Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a liver abscess. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
297474529761361392citrate transporterQuickGO ontologyBLASTP
297616029769307713-hydroxybutyrate dehydrogenaseQuickGO ontologyBLASTP
29769502977822873LysR family transcriptional regulatorQuickGO ontologyBLASTP
29779292978708780acetolactate decarboxylaseQuickGO ontologyBLASTP
297871829803971680acetolactate synthaseQuickGO ontologyBLASTP
29804212981191771acetoin reductaseQuickGO ontologyBLASTP
298147129825201050hypothetical proteinBLASTP
29825362982862327hypothetical protein
29829952983633639putative IS1400 transposase BQuickGO ontologyBLASTP
29838342984040207putative IS1400 transposase AQuickGO ontologyBLASTP
29841002984996897hypothetical proteinBLASTP
298500029861121113putative phage-related regulatory protein cIIQuickGO ontologyBLASTP
29877432988585843putative subunit of heme lyaseQuickGO ontologyBLASTP
29885822989040459putative subunit of heme lyaseQuickGO ontologyBLASTP
29890402989594555heme lyasedisulfide oxidoreductaseQuickGO ontologyBLASTP
298959129915431953cytochrome c-type biogenesis proteinQuickGO ontologyBLASTP
29915402991998459cytochrome c-type biogenesis heme-carrier proteinQuickGO ontologyBLASTP
29919822992212231heme exporter protein DQuickGO ontologyBLASTP
29922092992946738heme exporter protein CQuickGO ontologyBLASTP
29929962993655660heme exporter permease componentQuickGO ontologyBLASTP
29936522994275624cytochrome c biogenesis protein CcmAQuickGO ontologyBLASTP
299435929956991341putative gluconate dehydrogenase cytochrome c subunitQuickGO ontologyBLASTP
299571029974941785glucose-methanol-choline oxidoreductaseQuickGO ontologyBLASTP