Pre_GI Gene

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Host: NC_012731 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012731:2650603 Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a liver abscess. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
265060326516131011putative ribosexylosearabinosegalactoside ABC-type transport system permease componentQuickGO ontologyBLASTP
265161726526961080putative hydrolaseQuickGO ontologyBLASTP
26527112653466756hypothetical proteinBLASTP
265346626546081143putative acetylornithine deacetylaseQuickGO ontologyBLASTP
26547212655149429cell envelope integrity inner membrane proteinQuickGO ontologyBLASTP
26552542656045792putative enzymeQuickGO ontologyBLASTP
26561912657096906LysR family transcriptional regulatorQuickGO ontologyBLASTP
26571382658043906LysR family transcriptional regulatorQuickGO ontologyBLASTP
265814426593401197putative MFS-family transport proteinQuickGO ontologyBLASTP
26593982660018621amino acid homoserine exporterQuickGO ontologyBLASTP
266020426613101107fructose-mannitol-specific PTS family enzyme IIC componentQuickGO ontologyBLASTP
26613532661664312fructose-mannitol-specific PTS family enzyme IIB componentQuickGO ontologyBLASTP
26617212662191471fructose-mannitol-specific PTS family enzyme IIA componentQuickGO ontologyBLASTP
26623082662988681allulose-6-phosphate 3-epimeraseQuickGO ontologyBLASTP
266300926642711263PTS system ascorbate-specific transporter subunit IICQuickGO ontologyBLASTP
26643022664568267ascorbate-specific PTS family enzyme IIB componentQuickGO ontologyBLASTP
26645802665017438ascorbate-specific PTS family enzyme IIA componentQuickGO ontologyBLASTP
266522626662871062putative periplasmic binding proteinLacI transcriptional regulatorQuickGO ontologyBLASTP
266671126681321422putative permease of the major facilitator superfamilyQuickGO ontologyBLASTP
26681702668793624putative acetyltransferaseQuickGO ontologyBLASTP
26692772669924648TetR family transcriptional regulatorQuickGO ontologyBLASTP
266990026710001101putative ABC-type spermidineputrescine transport proteinQuickGO ontologyBLASTP
26712022672116915hypothetical proteinBLASTP
267215726733891233putative transporterQuickGO ontologyBLASTP
267366526752721608hypothetical proteinBLASTP
267538026764801101putative NADHflavin oxidoreductaseQuickGO ontologyBLASTP