Pre_GI Gene

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Host: NC_012667 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012667:839318 Vibrio cholerae MJ-1236 chromosome 2, complete genome

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae MJ-1236 is a toxigenic O1 El Tor Inaba strain from Matlab, Bangladesh, 1994 that represents the "Matlab variant" of El Tor. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
839318840109792Zn-dependent protease with chaperone functionQuickGO ontologyBLASTP
840277840729453hypothetical proteinBLASTP
840691840825135hypothetical protein
840730840963234phosphotransferase system IIA componentQuickGO ontologyBLASTP
8410448427411698SgrR sugar-phosphate stress transcriptional activator of SgrS small RNAQuickGO ontologyBLASTP
8430658451612097TonB-dependent heme and hemoglobin receptor HutAQuickGO ontologyBLASTP
845379846266888LysR family transcriptional regulatorQuickGO ontologyBLASTP
8463168489972682protein acetyltransferaseQuickGO ontologyBLASTP
849216849791576DamX-related proteinQuickGO ontologyBLASTP
8499428509461005D-alanyl-alanine synthetase AQuickGO ontologyBLASTP
851118851501384hypothetical proteinBLASTP
851509851820312translation initiation factor Sui1QuickGO ontologyBLASTP
852233852607375enterotoxin B subunitQuickGO ontologyBLASTP
852604853380777enterotoxin A subunit NAD--diphthamide ADP- ribosyltransferaseQuickGO ontologyBLASTP
8534798546781200zona occludens toxinQuickGO ontologyBLASTP
854675854965291accessory cholera enterotoxinQuickGO ontologyBLASTP
8549658561521188hypothetical proteinBLASTP
856259856507249colonization factorQuickGO ontologyBLASTP
856643857023381RstB phage-related integraseQuickGO ontologyBLASTP
8570048580831080RstA phage-related replication proteinQuickGO ontologyBLASTP
858206858550345cryptic phage CTXphi transcriptional repressor RstRQuickGO ontologyBLASTP
859020859172153hypothetical proteinBLASTP
859453859614162hypothetical proteinBLASTP
8596558608211167TraF-related proteinQuickGO ontologyBLASTP
860882861766885hypothetical proteinBLASTP
861769862506738transcriptional regulatorQuickGO ontologyBLASTP
8624008638991500signal transduction histidine kinaseQuickGO ontologyBLASTP