Pre_GI Gene

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Host: NC_012667 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012667:504534 Vibrio cholerae MJ-1236 chromosome 2, complete genome

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae MJ-1236 is a toxigenic O1 El Tor Inaba strain from Matlab, Bangladesh, 1994 that represents the "Matlab variant" of El Tor. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
503795504547753transcriptional regulator LuxR familyQuickGO ontologyBLASTP
50571350690611942-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
507740507940201L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
5090375100981062hypothetical proteinBLASTP
5101495112581110non-hemolytic enterotoxin lytic component L1QuickGO ontologyBLASTP
5112715123351065hypothetical proteinBLASTP
512347512742396hypothetical proteinBLASTP
512767513147381hypothetical proteinBLASTP
513776513937162phage integraseQuickGO ontologyBLASTP
5140455151211077hypothetical proteinBLASTP
515012515146135hypothetical protein
515421516365945DNA-binding transcriptional regulator DsdCQuickGO ontologyBLASTP
5165735178981326D-serine dehydrataseQuickGO ontologyBLASTP
518115518318204hypothetical proteinBLASTP
5191405202761137cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
5202895218811593cytochrome d ubiquinol oxidase subunit IQuickGO ontologyBLASTP
5220105234311422GntR family transcriptional regulatorQuickGO ontologyBLASTP
523666524616951D-alanyl-D-alanine endopeptidaseQuickGO ontologyBLASTP
52521052530596hypothetical protein
525570526223654outer membrane protein WQuickGO ontologyBLASTP